OXI Instruments, renowned for their forward-thinking approach to hybrid setups, present the E16 MIDI controller as a nerve center for complex rigs. This video dives into the E16’s capacity to assign dual destinations per encoder, enabling layered control over synths and effects. The walkthrough highlights not just the routing but also inventive ways to manipulate parameters—like inverted MIDI mappings—directly from the hardware. For those seeking hands-on, dynamic control in DAWless or live environments, this is a deep look into how the E16 reshapes performance workflow.

6. August 2026
LYRA
OXI Instruments E16: Dual MIDI Destinations Demystified
Big Time, Chroma Console, Novation Peak, OXI E16, OXI ONE MKII
The E16: Command Center for Hybrid MIDI Setups
The OXI E16 is introduced as a versatile MIDI controller, purpose-built to manage the intricacies of multi-device electronic music setups. OXI Instruments frames the E16 as a bridge between sequencers, synths, and effects, emphasizing its capacity to act as a central hub for both routing and live parameter control. In this demonstration, the E16 sits downstream from the OXI One MKII, sequencing a Novation Peak while simultaneously controlling parameters across the synth and two effect pedals.
The video details the MIDI routing: OXI One MKII’s MIDI out feeds the E16, which then passes data through a Chroma Console and Big Time pedal before reaching the Novation Peak. Each device is placed on its own MIDI channel, enabling clear differentiation and preventing message overlap. The E16’s ability to integrate seamlessly into such a chain is positioned as a core strength, making it an attractive proposition for users managing complex, performance-oriented rigs.
Dual Destinations: Mapping Power for Performance
Central to the E16’s appeal is its dual destination feature, allowing each encoder to transmit MIDI CC data to two different targets. The video demonstrates how this mapping flexibility enables the performer to control multiple parameters—across disparate devices—from a single hardware gesture. For example, one encoder can simultaneously adjust a synth’s filter cutoff and a pedal’s reverb amount, making complex sound design moves possible in real time.
This approach is not just about raw control, but about workflow efficiency. The video shows scenes and pages on the E16, each grouping relevant controls for effects or synth parameters. The ability to quickly flip between these groupings, and have every knob mapped for maximal impact, is highlighted as a way to keep the performer’s focus on music rather than menu-diving. OXI’s design philosophy—single-knob, multi-destination mapping—shines through in this hands-on demonstration.

"Oxy E16 allows you to set two destinations per encoder and you can do some interesting trick."
© Screenshot/Quote: Oxiinstruments (YouTube)
Creative Workflows: Inversion and Simultaneous Manipulation

"Basically I inverted the CC value so mean that when it's at zero it's sending out a value of 127 and when it's at 127 the Chroma Console gets a value of zero."
© Screenshot/Quote: Oxiinstruments (YouTube)
The real creative muscle of the E16 emerges in its approach to signal inversion and dual manipulation. The video walks through a practical scenario where an encoder is mapped such that turning it increases the wet level of a delay pedal while simultaneously extending the release on a synth. This is achieved by assigning one destination to increase as the knob turns right, and the other to decrease—effectively inverting the response for nuanced, performance-friendly morphing between states.
The presenter demonstrates setting minimum and maximum values for each MIDI destination, showing that you can invert one channel’s response while keeping the other “normal.” This is especially effective for creating evolving textures, such as opening a filter while reducing reverb, or linking tremolo depth with envelope release. The E16’s on-device configuration makes these mappings possible directly from the hardware, but the video notes that the companion app offers a more streamlined experience for deeper editing.
Scenes and Spontaneity: Performance Flexibility in Action
Switching between scenes and device groupings is fast and intuitive on the E16, supporting a performance style that thrives on spontaneity. The video demonstrates how users can move from shaping synth presets to manipulating effects, all with a tactile immediacy that keeps creative momentum high. The ability to record movements, group controls, and create snapshots is also mentioned, highlighting how the E16 facilitates not only live tweaking but the recall of complex states.
This approach empowers performers to navigate between subtle sound design tweaks and dramatic shifts, turning even a basic patch into a multi-dimensional soundscape. OXI’s integration of hands-on scene switching with dual-destination mapping positions the E16 as a serious tool for those seeking a fluid, dynamic command of their entire MIDI rig.

"I can have everything that I need in front of me."
© Screenshot/Quote: Oxiinstruments (YouTube)
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